By Andrej Čretnik (ed.)
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Extra resources for Achilles Tendon
20 Achilles Tendon Ker RF, Alexander RM, Bennett MB. Why are mammalian tendons so thick? J Zool 216: 309– 324, 1988. Kinugasa R, Hodgson JA, Edgerton VR, Shin DD, Sinha S. Reduction in tendon elasticity from unloading is unrelated to its hypertrophy. J Appl Physiol 109: 870–877, 2010. Kinugasa R, Shin D, Yamauchi J, Mishra C, Hodgson JA, Edgerton VR, Sinha S. Phasecontrast MRI reveals mechanical behavior of superficial and deep aponeuroses in human medial gastrocnemius during isometric contraction.
Although some of the tested variants were non-synonymous (changed an amino acid in the protein), we cannot exclude the possibility that other untested variants within Gene Variants that Predispose to Achilles Tendon Injuries: An Update on Recent Advances 33 COL12A1 and COL14A1 are associated with Achilles tendinopathy. Interestingly the variants within the COL12A1 gene were however associated with ACL ruptures in females (Posthumus et al, 2010). The association of other genes encoding for proteins involved in fibrillogenesis remains to be tested.
Genetic risk factors for Achilles tendon injuries. International SportMed Journal, 7(3), 201–215. , Schwellnus, M. , Noakes, T. , & Collins, M. (2008). The COL12A1 and COL14A1 genes and Achilles tendon injuries. International journal of sports medicine, 29(3), 257–263. Gene Variants that Predispose to Achilles Tendon Injuries: An Update on Recent Advances 39 September AV, Schwellnus, M. , & Collins, M. (2007). Tendon and ligament injuries: the genetic component. British Journal of Sports Medicine, 41(4), 241–246.
Achilles Tendon by Andrej Čretnik (ed.)