Ciba Foundation Symposium - Internal Secretions of the - download pdf or read online

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ISBN-10: 0470718978

ISBN-13: 9780470718971

ISBN-10: 0470722401

ISBN-13: 9780470722404

Content:
Chapter 1 Chairman's establishing comments (page 1):
Chapter 2 Morphological reviews of the Destruction of ??Cells through Chemical potential (pages 2–13): Helmu Ferner
Chapter three Metabolic results of ??Cell Destruction (pages 14–34): Claus V. Holt, Linde V. Holt, Barbara Kroner and Joachim Kuhnau
Chapter four Pituitary progress Hormone and Blood Insulin task (pages 35–54): P. J. Randle
Chapter five The keep an eye on of the Secretory task of the Islets of Langerhans (pages 55–74): Piero P. Foa
Chapter 6 the results of Hypophysectomy and of lengthy progress Harmone management at the Pancreatic ??Cells of the Rat (pages 75–88): Martin G. Goldner and Bruno W. Volk
Chapter 7 Fractionation of Insulin (pages 89–109): Eugene Fredericq
Chapter eight The Chemical constitution of Insulin (pages 110–121): F. Sange
Chapter nine an idea of the Three?Dimensional constitution of Insulin (pages 122–132): David F. Waugh
Chapter 10 A hypothesis on Insulin (pages 133–146): Dorothy Crowfoot Hodgkin and Beryl Oughton
Chapter eleven Insulin and Glucagon (pages 147–166): Werner Scrulze
Chapter 12 Chemical and organic features of Glucagon (pages 167–178): Otto okay. Behrens, A. Staub, Marry A. Root and W. W. Bromer
Chapter thirteen The motion of Glucagon on Liver Phosphorylase (pages 179–193): E. W. Sutherland, W. D. Wosilait and T. W. Rall
Chapter 14 Inhibitory impression of Glucagon at the Insulin Glucose Uptake of the remoted Diaphragm of the Rat (pages 194–202): J. L. R. Candela and R. R. Candela
Chapter 15 The Hepatic motion of Insulin (pages 203–226): Christian De Duve
Chapter sixteen a few difficulties of Permeability of Tissue Cells to Sugars (pages 227–239): Ernst Helmreich and Carl F. Cori
Chapter 17 The shipping of Glucose and different Sugars throughout mobile Membranes and the impression of Insulin (pages 240–265): C. R. Park, R. L. submit, C. F. Kalman, J. H. Wright, L. H. Johnson and H. E. Morgan
Chapter 18 Pancreatic Islets and progress (pages 266–284): Cesare Cavallero
Chapter 19 Chairman's ultimate comments (pages 285–287):

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Extra resources for Ciba Foundation Symposium - Internal Secretions of the Pancreas (Colloquia on Endocrinology), Volume 9

Sample text

In the course of a-cell destruction by synthalin or IPTD, rabbits as well as rats developed a severe hypoglycaemia and often fatal shock unless glucose was given. 14 METABOLICEFFECTS OF &-CELL DESTRUCTION 15 Twenty to twenty-four hours after the injection of synthalin we found a total loss of glucagon in the pancreas of rats, which showed severe hypoglycaemia and shock, similar to those rats in which we found widespread damage of a-cells (Table I). /KG. /KG. INTRAPERITONEALLY). 4 10 21 In the case of IPTD-treated animals there was a marked diminution of glucagon.

I wonder whether anyone has repeated them and whether there is any possible connection with the difference between the a :p-cell ratio of the pancreas of the young animal and that of the adult. Goldner: A similar phenomenon has been seen in alloxan diabetes. Young and growing animals are not infrequently resistant to an otherwise diabetogenic dose of alloxan. Schulze: This might be due to the change in enzymatic power of blood and tissues with respect to destruction of insulin, which was shown by Burger to decrease with the progress of ageing.

7439. Earlier experiments suggested that the slope of the log. doselresponse curve was constant (Randle, 1954c, 1955), but more recently significant variations in slope have been demonst. 1080 to strated (range of slopes 1 1661 rt 0 * 1261). The estimates of plasma insulin activity obtained by a single standard method (Randle, 1954c) are therefore only approximate estimates. -+ Influence of growth hormone on plasma insulin activity The insulin activity of plasma from five intact cats treated with saline was, in every instance, significantly less than 16 milliunits/ml.

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Ciba Foundation Symposium - Internal Secretions of the Pancreas (Colloquia on Endocrinology), Volume 9


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