Ciba Foundation Symposium - Ionizing Radiations and Cell - download pdf or read online

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By Ciba Foundation, G E. W. Wolstenholme, Cecilia M. 1927- O'Connor

ISBN-10: 0470719001

ISBN-13: 9780470719008

ISBN-10: 0470722436

ISBN-13: 9780470722435

Content:
Chapter 1 Chairman's commencing comments (pages 1–2): A. Haddow
Chapter 2 Cytoplasmic and Nuclear constitution with regards to Metabolic actions (pages 3–24): J. Bracket
Chapter three the consequences of Ionizing Radiations on Enzymes in vitro (pages 25–37): W. M. Dale
Chapter four The job of Enzymes and Coenzymes in Irradiated Tissues (pages 38–58): Antoinette Pirie
Chapter five results of X?Rays and Radiomimetic brokers on Nucleic Acids and Nucleoproteins (pages 59–76): J. A. V. Butler
Chapter 6 Oxidative Phosphorylation in a few Radiosensitive Tissues After Irradiation (pages 77–91): D. W. van Bekkum
Chapter 7 the results of Extraneous brokers on mobile Metabolism (pages 92–105): H. A. Krebs
Chapter eight The impression of Oxygen on Radiation results (pages 106–119): H. Laser
Chapter nine The impact of Chemical Pre? and Post?Treatments on Radiosensitivity of micro organism, and Their importance for larger Organisms (pages 120–139): Alexander Hollaender and George E. Stapleton
Chapter 10 Postirradiation therapy of Mice and Rats (pages 140–160): D. W. H. Barnes and J. F. Loutit
Chapter eleven reports at the Mechanism of Protein Synthesis (pages 161–173): P. C. Zamecnik, Elizabeth B. Keller, M. B. Hoagland, J. W. Littlefield and R. B. Loftfield
Chapter 12 Nucleic Acids and Amino Acid Incorporation (pages 174–184): E. F. Gale
Chapter thirteen Protein Synthesis in Protoplasts (pages 185–195): S. Spiegelman
Chapter 14 impression of Radiation on DNA Metabolism (pages 196–211): Alma Howard
Chapter 15 The impression of Radiation at the Metabolism of Ascites Tumour Cells (pages 212–224): Arne Forssberg
Chapter sixteen impact of Radiation on Metabolism of Regenerating Rat Liver (pages 225–238): Barbara E. Holmes
Chapter 17 The Induction of Chromosomal Aberrations by way of Ionizing Radiations and Chemical Mutagens (pages 239–254): C. P. Swanson and Bengt Kihlman
Chapter 18 fundamental websites of strength Deposition linked to Radiobiologigal Lesions (pages 255–274): L. H. Gray
Chapter 19 results of Radiation and Peroxides on Viral and Bacterial services associated with DNA Specificity (pages 275–308): Raymond Latarjet

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Content material: bankruptcy 1 Chairman's beginning feedback (pages 1–2): A. HaddowChapter 2 Cytoplasmic and Nuclear constitution in terms of Metabolic actions (pages 3–24): J. BracketChapter three the results of Ionizing Radiations on Enzymes in vitro (pages 25–37): W. M. DaleChapter four The job of Enzymes and Coenzymes in Irradiated Tissues (pages 38–58): Antoinette PirieChapter five results of X?

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Extra resources for Ciba Foundation Symposium - Ionizing Radiations and Cell Metabolism

Sample text

EfSect of a-radiation. With regard to the effect of radiation of different ionization density, only one extensive study on the effect of u-radiation as compared with X-radiation, on carboxypeptidase, has been carried out (Dale, Gray and Meredith, 1949). The result was that the efficiency of u-rays was shown to be only one twentieth that of X-rays, and this low efficiency could be accounted for by the &radiation which accompanies the a-radiation, and is similar in ion density to X-radiation. We havc so far dealt with enzymes and co-solutes in solution.

1955). I n TheNucleic Acids, p. 199. New York: Academic Press. HOLLOWAY, B. , and RIPLEY,S. H. (1952). J. biol. , 196, 695. , and LBVTRUP,S. (1949). R. Lab. Carlsberg, 27, 27. , and POLLOCK, B. M. (1952). R. Lab. Carlsberg, 28, 211. HULTIN, T. (1950). Exp. , 1, 376. HURLBERT, R. , and POTTER, V. R. (1952). J. biol. , 195, 257. JAMES, T. W. (1954). Biochim. biophys. mta, 15, 367. , and SZAFARZ, D. (1950). Arch. , 26, 54. KORITZ,S. , and CHANTRENNE,H. (1954). Biochim. biophys. acta, 13, 209. , and BORSOOK, H.

Bracliet : Our observations were made under aerobic conditions. It will be difficult to test the effects of anaerobic conditions because, in order to measure the DPN content of Amoeba, using a very sensitive method, we have t o cut about 6 5 , 0 0 0 amoebae for each experiment. What we would really like to know is whether the distribution of DPN would be altered in non-nucleated cytoplasm: there is a possibility that part of the DPN may be linked t o mitochondria. Perhaps only the free DPN is attacked, while the DPN bound to the mitochondria is more or less preserved.

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Ciba Foundation Symposium - Ionizing Radiations and Cell Metabolism by Ciba Foundation, G E. W. Wolstenholme, Cecilia M. 1927- O'Connor


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