By Michael H. Ebert;Peter T. Loosen;Barry Nurcombe;James F. Leckman
The main available, built-in resource of scientific psychiatric information--completely up to date! present analysis & remedy: Psychiatry, moment variation is the final word reference for quick answering day by day questions about psychiatric sickness in either adults and kids. entire in scope, but streamlined in its insurance, this time-saving medical significant other studies crucial psychopharmacologic and psychotherapeutic methods to the complete diversity of psychiatric problems. gains the simplest interviewing options and methods very important assessment, trying out, and decision-making instruments and standards Ready-to-use info on psychiatry and the legislations, mental checking out, emergency psychiatry, comparing babies, and extra Authoritative insurance of developmental psychology, neuropsychopharmacology, psychiatric genetics, psychoanalysis, and different comparable parts useful part at the ideas of comparing and diagnosing sufferers, in addition to therapy options center sections on grownup problems and pediatric psychiatric difficulties NEW! severe updates to key diagnostic, psychopharmacologic, and psychotherapeutic modalities NEW! part on psychiatric perform in specific settings (20081118)
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Additional info for CURRENT Diagnosis & Treatment: Psychiatry, Second Edition (LANGE CURRENT Series)
Among single gene causes of mental retardation, Koranyi listed five dominant diseases (tuberous sclerosis, neurofibromatosis, Sturgeâ Weber disease, von Hippel-Lindow, and craniosynostosis), and four recessive diseases (Hurlerâ Hunter disease, galactosemia, G-6 phosphodehydrogenase deficiency and familial hypoglycemia), as well as three recessive aminoaciduria and three lipid-related disorders. Many more are listed in McKusick's compendium Mendelian Inheritance in Man. 5 persons per 1000 and is the most common single cause of the condition.
Table 3â 3. , 1995. , 1992 Twin Studies A total of 81 twin pairs, where at least one member is affected with Alzheimer disease (AD), have been reported in the literature. The MZ concordance rate (approximately 45%) is not different from the DZ concordance rate (approximately 35%) in these studies. Family Studies Most of the relatives of later-onset AD probands will have died of other causes before passing the age of risk. However, the risk to siblings of probands (with an affected parent) whose age of onset was less than 70 years is close to 50%.
Of those, 4 out of 5 males will express the clinical phenotype as compared with 1 out of 3 females (some homozygotes are nonpenetrant and some heterozygotes are penetrant). Genetic tests are now available to determine carrier status in nonpenetrant individuals. 3 region is now known to be a triplet repeat of variable length. Increased numbers of repeats (associated with greater severity of illness) occur as the gene is passed to succeeding generations. When the number of repeats exceeds a threshold, clinical manifestations are seen.
CURRENT Diagnosis & Treatment: Psychiatry, Second Edition (LANGE CURRENT Series) by Michael H. Ebert;Peter T. Loosen;Barry Nurcombe;James F. Leckman