New PDF release: Cytologic Detection of Urothelial Lesions

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By Dorothy L. Rosenthal MD, FIAC, Stephen S. Raab MD (auth.)

ISBN-10: 0387239456

ISBN-13: 9780387239453

ISBN-10: 0387239472

ISBN-13: 9780387239477

The Essentials in Cytopathology sequence publishes generously illustrated and undemanding publications with over a hundred complete colour photos that illustrate ideas and perform in Cytopathology for pathologists and clinicians.

Cytologic Detection of Urothelial Lesions by means of Dorothy L. Rosenthal, MD and Stephen S. Raab, MD is the second one quantity within the Series. This quantity will current an easy method of facing mobile samples from the urinary tract.

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2. (600x) 38 2. 16. Reactive Urothelial Cells—bladder washing: A cluster of reactive urothelial cells is seen. The cells are admixed with acute inflammatory cells and show either marked nuclear hyperchromasia and degeneration or a prominent nucleolus. 17. Reactive Urothelial Cells—catheterized urine: These superficial reactive urothelial cells show homogeneous cytoplasm and mildly hyperchromatic nuclei. Note the low nuclear to cytoplasmic ratio, acute inflammation and bacteria in the background. (600x) 40 2.

In this case, degenerated nuclei are admixed with smaller, hyperchromatic benign urothelial cells. 3. Benign Urothelial Cells—catheterized urine: A cluster of benign urothelial cells is admixed with a few squamous cells. The urothelial cells exhibit a moderately increased nuclear to cytoplasmic ratio although the nuclei are relatively uniform to slightly irregular in contour. The cells contain a variable chromatin pattern and the cytoplasm is homogeneous (absence of vacuoles). Clusters of benign urothelial cells in catheterized urine specimens should not be mistaken for low or high grade urothelial carcinoma.

600x) 34 2. 12. Reactive Urothelial Cells—bladder washing: Sheets of epithelial cells may be misinterpreted as neoplastic. Careful examination of nuclear criteria, such as pale chromatin, prominent nucleoli, low NC ratios, and a background of acute inflammation, contributes to the interpretation of reactive/inflammatory cellular changes. 13. Reactive Urothelial Cells—bladder washing: These urothelial cells show slightly increased nuclear to cytoplasmic ratios and variably sized nuclei. The cytoplasm is homogeneous and only mildly atypical.

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Cytologic Detection of Urothelial Lesions by Dorothy L. Rosenthal MD, FIAC, Stephen S. Raab MD (auth.)

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