By Dorothy L. Rosenthal MD, FIAC, Stephen S. Raab MD (auth.)
The Essentials in Cytopathology sequence publishes generously illustrated and undemanding publications with over a hundred complete colour photos that illustrate ideas and perform in Cytopathology for pathologists and clinicians.
Cytologic Detection of Urothelial Lesions by means of Dorothy L. Rosenthal, MD and Stephen S. Raab, MD is the second one quantity within the Series. This quantity will current an easy method of facing mobile samples from the urinary tract.
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Extra resources for Cytologic Detection of Urothelial Lesions
2. (600x) 38 2. 16. Reactive Urothelial Cells—bladder washing: A cluster of reactive urothelial cells is seen. The cells are admixed with acute inﬂammatory cells and show either marked nuclear hyperchromasia and degeneration or a prominent nucleolus. 17. Reactive Urothelial Cells—catheterized urine: These superﬁcial reactive urothelial cells show homogeneous cytoplasm and mildly hyperchromatic nuclei. Note the low nuclear to cytoplasmic ratio, acute inﬂammation and bacteria in the background. (600x) 40 2.
In this case, degenerated nuclei are admixed with smaller, hyperchromatic benign urothelial cells. 3. Benign Urothelial Cells—catheterized urine: A cluster of benign urothelial cells is admixed with a few squamous cells. The urothelial cells exhibit a moderately increased nuclear to cytoplasmic ratio although the nuclei are relatively uniform to slightly irregular in contour. The cells contain a variable chromatin pattern and the cytoplasm is homogeneous (absence of vacuoles). Clusters of benign urothelial cells in catheterized urine specimens should not be mistaken for low or high grade urothelial carcinoma.
600x) 34 2. 12. Reactive Urothelial Cells—bladder washing: Sheets of epithelial cells may be misinterpreted as neoplastic. Careful examination of nuclear criteria, such as pale chromatin, prominent nucleoli, low NC ratios, and a background of acute inﬂammation, contributes to the interpretation of reactive/inﬂammatory cellular changes. 13. Reactive Urothelial Cells—bladder washing: These urothelial cells show slightly increased nuclear to cytoplasmic ratios and variably sized nuclei. The cytoplasm is homogeneous and only mildly atypical.
Cytologic Detection of Urothelial Lesions by Dorothy L. Rosenthal MD, FIAC, Stephen S. Raab MD (auth.)